Article
Role of SLV in SLI substrate recognition by the Neurospora VS ribozyme.
RNA (New York, N.Y.) - 1 Apr 2008
Bouchard Patricia, Lacroix-Labonté Julie, Desjardins Geneviève, Lampron Philipe, Lisi Véronique, Lemieux Sébastien, Major François, Legault Pascale
Abstract excerpt
Substrate recognition by the VS ribozyme involves a magnesium-dependent loop/loop interaction between the SLI substrate and the SLV hairpin from the catalytic domain. Recent NMR studies of SLV demonstrated that magnesium ions stabilize a U-turn loop structure and trigger a conformational change f...
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