Mutational potentiality of stannous chloride: an important reducing agent in the Tc-99m-radiopharmaceuticals.

doi:10.1016/s0921-8777(98)00026-3

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Article

Mutational potentiality of stannous chloride: an important reducing agent in the Tc-99m-radiopharmaceuticals.

Mutation research - 7 Aug 1998

Cabral R E, Leitão A C, Lage C, Caldeira-de-Araújo A, Bernardo-Filho M, Dantas F J, Cabral-Neto J B

Abstract excerpt

Stannous chloride (SnCl2) is frequently used in nuclear medicine as a reducing agent to label many radiopharmaceutical products with technetium-99m (99mTc). The aim of the present paper was to study the role of DNA repair genes in the repair of SnCl2-induced damage, using mutant strains of Escher...

Topics

DNA Damage
DNA Repair
Escherichia coli
Exodeoxyribonucleases
Mutation
Organotechnetium Compounds
Tin Compounds

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