Article
Intracellular trafficking of the vacuolar H+-ATPase accessory subunit Ac45.
Journal of cell science - 1 Oct 1998
Jansen E J, Holthuis J C, McGrouther C, Burbach J P, Martens G J
Abstract excerpt
Ac45 is a type I transmembrane protein associated with vacuolar H+-ATPase, a proton pump mediating the acidification of multiple intracellular organelles. In this study, we examined the intracellular routing of Ac45 in transfected CV-1 fibroblasts. Steady state immunolabeling showed that Ac45 is...
Topics
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Biological Transport
- Cell Line
- Cell Membrane
- Cytoplasm
- DNA Mutational Analysis
- Endocytosis
- Intracellular Membranes
- Membrane Proteins
- Microscopy, Fluorescence
- Molecular Sequence Data
- Mutation
- Protein Sorting Signals
- Proton-Translocating ATPases
- Receptors, Interleukin-2
- Recombinant Fusion Proteins