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Article

Intracellular trafficking of the vacuolar H+-ATPase accessory subunit Ac45.

Journal of cell science - 1 Oct 1998

Jansen E J, Holthuis J C, McGrouther C, Burbach J P, Martens G J

Abstract excerpt

Ac45 is a type I transmembrane protein associated with vacuolar H+-ATPase, a proton pump mediating the acidification of multiple intracellular organelles. In this study, we examined the intracellular routing of Ac45 in transfected CV-1 fibroblasts. Steady state immunolabeling showed that Ac45 is located on the plasma membrane and in a vacuolar compartment in the juxtanuclear region. Antibody internalization...

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Identifiers

PMID: 9739073
DOI: 10.1242/jcs.111.20.2999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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