Article
VAMP4 cycles from the cell surface to the trans-Golgi network via sorting and recycling endosomes.
Journal of cell science - 15 Mar 2007
Tran Ton Hoai Thi, Zeng Qi, Hong Wanjin
Abstract excerpt
VAMP4 is enriched in the trans-Golgi network (TGN) and functions in traffic from the early and recycling endosomes to the TGN, but its trafficking itinerary is unknown. Cells stably expressing TGN-enriched VAMP4 C-terminally-tagged with EGFP (VAMP4-EGFP) are able to internalize and transport EGFP antibody efficiently to the TGN, suggesting that VAMP4-EGFP cycles between the cell surface and the TGN. The...
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