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Article

Cytogenetic analysis of pancreatic carcinomas: Intratumor heterogeneity and nonrandom pattern of chromosome aberrations

1 Oct 1998

Abstract excerpt

Twenty-nine nonendocrine pancreatic carcinomas (20 primary tumors and nine metastases) were studied by chromosome banding after short-term culture. Acquired clonal aberrations were found in 25 tumors and a detailed analysis of these revealed extensive cytogenetic intratumor heterogeneity. Apart from six carcinomas with one clone only, 19 tumors displayed from two to 58 clones, bringing the total number of clones...

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Share to Genomic variations and chromosomal abnormalities
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PMID: 9739011
DOI: 10.1002/(sici)1098-2264(199810)23:2<81::aid-gcc1>3.0.co;2-0

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