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Establishment and characterization of 4 new human pancreatic cancer cell lines: evidences of different tumor phenotypes.

Pancreas - 1 Mar 2009

Chifenti Barbara, Morelli Mariangela, Zavaglia Michele, Coviello Domenico A, Guerneri Silvana, Santucci Annalisa, Paffetti Alessandro, Masetti Massimo, Locci Maria Teresa, Bertacca Gloria, Capodanno Alessandra, Collecchi Paola, Campani Daniela, Mosca Franco, Bevilacqua Generoso, Cavazzana Andrea O

Abstract excerpt

OBJECTIVES: Pancreatic cancer still remains a challenge for its biological complexity and lack of effective therapeutic strategies. Establishing new pancreatic cancer cell lines is therefore of paramount importance to clarify its biology. METHODS: We established and characterized 4 new pancreatic cancer cell lines (PP78, PP109, PP117, and PP161) according to their genetic (K-Ras, TP53, CDKN2A, and MADH4; DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19002021
DOI: 10.1097/MPA.0b013e31818c746a

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