Article
Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor.
The Journal of biological chemistry - 25 Sept 1998
Murray S R, Evans C J, von Zastrow M
Abstract excerpt
Opioid receptors are regulated within minutes after activation by G protein-coupled receptor kinase-mediated phosphorylation and dynamin-dependent endocytosis. We addressed the question of whether phosphorylation is required for opioid receptor endocytosis by examining a functional, truncated mut...
Topics
- Animals
- CHO Cells
- Cell Line
- Clathrin
- Cricetinae
- Dynamins
- Endocytosis
- Enzyme-Linked Immunosorbent Assay
- Flow Cytometry
- GTP Phosphohydrolases
- Humans
- Microscopy, Fluorescence
- Mutation
- Phosphorylation
- Receptors, Opioid