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Article

Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor.

The Journal of biological chemistry - 25 Sept 1998

Murray S R, Evans C J, von Zastrow M

Abstract excerpt

Opioid receptors are regulated within minutes after activation by G protein-coupled receptor kinase-mediated phosphorylation and dynamin-dependent endocytosis. We addressed the question of whether phosphorylation is required for opioid receptor endocytosis by examining a functional, truncated mutant delta opioid receptor (DOR344T), which is missing phosphorylation sites located in the carboxyl-terminal...

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Identifiers

PMID: 9737953
DOI: 10.1074/jbc.273.39.24987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor.PMID 9737953Read ↗

A phosphorylation-regulated brake mechanism controls the initial endocytosis of opioid receptors but is not required for post-endocytic sorting to lysosomes.Semantic proximity Read ↗

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