Article
Lack of association between neuroleptic malignant syndrome and polymorphisms in the 5-HT1A and 5-HT2A receptor genes.
The American journal of psychiatry - 1 Sept 1998
Kawanishi C, Hanihara T, Shimoda Y, Suzuki K, Sugiyama N, Onishi H, Miyakawa T, Yamada Y, Kosaka K
Abstract excerpt
OBJECTIVE: The molecular basis of neuroleptic malignant syndrome is unclear, but studies suggest that genetic factors are involved in its pathogenesis. Considering possible involvement of the serotonergic system in neuroleptic malignant syndrome, the authors examined the association between neuro...
Topics
- Adult
- Alleles
- Cardiopulmonary Resuscitation
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Neuroleptic Malignant Syndrome
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Psychotropic Drugs
- Receptors, Serotonin
- Risk Factors
- Serotonin