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Article

Negative association between T102C polymorphism of the 5-HT2a receptor gene and schizophrenia in Japan.

Human heredity - 1 Jan 2000

Shinkai T, Ohmori O, Kojima H, Terao T, Suzuki T, Abe K

Abstract excerpt

Serotonin (5-hydroxytryptamine, 5-HT) may play an important role in the pathogenesis of schizophrenia. Previous studies suggested that the efficacy of atypical neuroleptic drugs (e.g., risperidone and clozapine) on negative symptoms may be related to the 5-HT2a receptor. Although association stud...

Topics

Adolescent
Adult
Aged
Alleles
Female
Gene Frequency
Genotype
Humans
Japan
Male
Middle Aged
Polymorphism, Genetic
Receptors, Serotonin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizophrenia

Source

Identifiers

PMID: 9694252
DOI: 10.1159/000022803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9694252-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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