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Article

Negative association between T102C polymorphism of the 5-HT2a receptor gene and schizophrenia in Japan.

Human heredity - 1 Jan 2000

Shinkai T, Ohmori O, Kojima H, Terao T, Suzuki T, Abe K

Abstract excerpt

Serotonin (5-hydroxytryptamine, 5-HT) may play an important role in the pathogenesis of schizophrenia. Previous studies suggested that the efficacy of atypical neuroleptic drugs (e.g., risperidone and clozapine) on negative symptoms may be related to the 5-HT2a receptor. Although association studies between MspI polymorphism (T102C) and the 5-HT2a receptor gene and schizophrenia have been reported, their results...

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PMID: 9694252
DOI: 10.1159/000022803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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