Article
Susceptibility to neuroleptic-induced tardive dyskinesia and the T102C polymorphism in the serotonin type 2A receptor.
Biological psychiatry - 15 Jul 2001
Tan E C, Chong S A, Mahendran R, Dong F, Tan C H
Abstract excerpt
BACKGROUND: Genetic factors have been implicated in the pathophysiology of the movement disorder tardive dyskinesia, which may involve dopamine-serotonin interaction. Case-control association studies have identified the T102C polymorphism of the 5-HT2A receptor gene as being associated with schizophrenia and responsiveness to clozapine. In this study, we examine the association of this polymorphism in the 5-HT2A...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.