Article
Herpes simplex virus type 1 glycoprotein gC mediates immune evasion in vivo.
Journal of virology - 1 Oct 1998
Lubinski J M, Wang L, Soulika A M, Burger R, Wetsel R A, Colten H, Cohen G H, Eisenberg R J, Lambris J D, Friedman H M
Abstract excerpt
Many microorganisms encode proteins that interact with molecules involved in host immunity; however, few of these molecules have been proven to promote immune evasion in vivo. Herpes simplex virus type 1 (HSV-1) glycoprotein C (gC) binds complement component C3 and inhibits complement-mediated vi...
Topics
- Animals
- Cell Fusion
- Cells, Cultured
- Chlorocebus aethiops
- Complement C3
- Dogs
- Guinea Pigs
- Mice
- Mice, Knockout
- Mutation
- Phenotype
- Simplexvirus
- Vero Cells