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Article

Mutant p53 reactivator SLMP53-2 hinders ultraviolet B radiation-induced skin carcinogenesis.

Pharmacological research - 1 Jan 2022

Loureiro Joana B, Ribeiro Rita, Nazareth Nair, Ferreira Tiago, Lopes Elizabeth A, Gama Adelina, Machuqueiro Miguel, Alves Marco G, Marabini Laura, Oliveira Paula A, Santos Maria M M, Saraiva Lucília

Abstract excerpt

The growing incidence of skin cancer (SC) has prompted the search for additional preventive strategies to counteract this global health concern. Mutant p53 (mutp53), particularly with ultraviolet radiation (UVR) signature, has emerged as a promising target for SC prevention based on its key role in skin carcinogenesis. Herein, the preventive activity of our previously disclosed mutp53 reactivator SLMP53-2 against...

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Identifiers

PMID: 34890775
DOI: 10.1016/j.phrs.2021.106026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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