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Article

The evolution of progesterone receptor ligands

29 Sept 2006

Abstract excerpt

Progesterone is one of the first nuclear receptor hormones to be described functionally and subsequently approached as a drug target. Because progesterone (1) affects both menstruation and gestation via the progesterone receptor (PR), research aimed at modulating its activity is usually surrounded by controversy. However, ligands for PR were developed into drugs, and their evolution can be crudely divided into...

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PMID: 17013809
DOI: 10.1002/med.20083

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