Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stimulation of Mouse and Human Primitive Hematopoiesis by Murine Embryonic Aorta-Gonad-Mesonephros–Derived Stromal Cell Lines

15 Sept 1998

Abstract excerpt

We report here on a novel stromal cell line, AGM-S3, derived from the aorta-gonad-mesonephros (AGM) region of a 10.5 days postcoitum (dpc) mouse embryo. The AGM-S3 cells promoted production of hematopoietic progenitors and day-12 spleen colony-forming cells from Lin-c-Kit+Sca-1(+) murine primitive hematopoietic cells. They also supported for 6 weeks generation of human multipotential progenitors from cord blood...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Pluripotent Stem Cells Research
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9731061
DOI: 10.1182/blood.v92.6.2032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stimulation of Mouse and Human Primitive Hematopoiesis by Murine Embryonic Aorta-Gonad-Mesonephros–Derived Stromal Cell LinesPMID 9731061Read ↗

Differential hematopoietic supportive potential and gene expression of stroma cell lines from midgestation mouse placenta and adult bone marrow.Semantic proximity Read ↗

Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros regionSemantic proximity Read ↗

Stromal cell lines from the aorta-gonado-mesonephros region are potent supporters of murine and human hematopoiesisSemantic proximity Read ↗

Induction of a hemogenic program in mouse fibroblasts.Semantic proximity Read ↗

Development of Hematopoietic Stem Cells in the Human EmbryoSemantic proximity Read ↗

Molecular Profile and Partial Functional Analysis of Novel Endothelial Cell‐Derived Growth Factors that Regulate HematopoiesisSemantic proximity Read ↗

Enforced activation of STAT5A facilitates the generation of embryonic stem-derived hematopoietic stem cells that contribute to hematopoiesis in vivo.Semantic proximity Read ↗

Detailed characterization of the human aorta‐gonad‐mesonephros region reveals morphological polarity resembling a hematopoietic stromal layerSemantic proximity Read ↗

Recent Advances in Developmental Hematopoiesis: Diving Deeper With New Technologies.Semantic proximity Read ↗

Identification of the niche and phenotype of the first human hematopoietic stem cells.Semantic proximity Read ↗

Efficient Hematopoietic Differentiation of Human Embryonic Stem Cells on Stromal Cells Derived from Hematopoietic NichesSemantic proximity Read ↗

Early Development of Definitive Erythroblasts from Human Pluripotent Stem Cells Defined by Expression of Glycophorin A/CD235a, CD34, and CD36.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.