Article
Deletion insertion polymorphism of the angiotensin converting enzyme gene and progression of diabetic nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 1997
Björck S, Blohmé G, Sylvén C, Mulec H
Abstract excerpt
BACKGROUND: The activity in the renin angiotensin system is important for the progression of diabetic nephropathy. Genetic abnormalities in this system have been suggested as a risk factor for the development and progression of diabetic nephropathy. The homozygous DD (deletion) genotype of the angiotensin-converting enzyme gene has been associated with increased circulating angiotensin converting enzyme and a...
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