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Article

Commissureless endocytosis is correlated with initiation of neuromuscular synaptogenesis.

Development (Cambridge, England) - 1 Oct 1998

Wolf B, Seeger M A, Chiba A

Abstract excerpt

We show that the Commissureless (COMM) transmembrane protein is required at neuromuscular synaptogenesis. All muscles in the Drosophila embryo express COMM during the period of motoneuron-muscle interaction. It is endocytosed into muscles before synaptogenesis. In comm loss-of-function mutants, m...

Topics

Animals
Drosophila
Drosophila Proteins
Endocytosis
Gene Expression Regulation, Developmental
Genes, Insect
Growth Cones
Immunohistochemistry
Insect Proteins
Membrane Proteins
Models, Neurological
Motor Neurons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nerve Tissue Proteins

Neuromuscular Junction

Phenotype

Synapses

Source

Identifiers

PMID: 9729493
DOI: 10.1242/dev.125.19.3853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9729493-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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