Article
Neuromuscular synaptogenesis in wild-type and mutant zebrafish.
Developmental biology - 15 Sept 2005
Panzer Jessica A, Gibbs Sarah M, Dosch Roland, Wagner Daniel, Mullins Mary C, Granato Michael, Balice-Gordon Rita J
Abstract excerpt
Genetic screens for synaptogenesis mutants have been performed in many organisms, but few if any have simultaneously screened for defects in pre- and postsynaptic specializations. Here, we report the results of a small-scale genetic screen, the first in vertebrates, for defects in synaptogenesis. Using zebrafish as a model system, we identified seven mutants that affect different aspects of neuromuscular synapse...
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