Article
Nerve growth factor stimulates diacylglycerol de novo synthesis and phosphatidylinositol hydrolysis in pheochromocytoma cells.
Brain research - 24 Aug 1998
Li J, Wurtman R J
Abstract excerpt
Induction of neurite outgrowth by treating pheochromocytoma cells (PC12 cells) with nerve growth factor (NGF) is associated with major increases in cellular levels of diacylglycerol (DAG), an essential and probably limiting precursor in phosphatidylcholine (PC) and phosphatidylethanolamine (PE) s...
Topics
- Animals
- Cell Differentiation
- Diglycerides
- Glycerol
- Hydrolysis
- Lipid Metabolism
- Lipids
- Nerve Growth Factors
- Oleic Acid
- PC12 Cells
- Phenotype
- Pheochromocytoma
- Phosphatidylinositols
- Phospholipids
- Rats
- Time Factors
- Triazenes
- Tritium