Article
Langerhans cells are susceptible to measles virus infection and actively suppress T cell proliferation.
European journal of dermatology : EJD - 1 Sept 1998
Steineur M P, Grosjean I, Bella C, Kaiserlian D
Abstract excerpt
We have previously reported that the measles virus (MV) could productively infect human dendritic cells (DC), derived in vitro from CD34+ cord blood progenitors in the presence of GM-CSF and TNF-alpha. In this study, we provide evidence that freshly isolated Langerhans cells (LC), which are immat...
Topics
- Antigens, Viral
- CD4-Positive T-Lymphocytes
- Cell Division
- Cells, Cultured
- Epidermal Cells
- Epidermis
- Giant Cells
- Humans
- Immune Tolerance
- Immunity, Cellular
- Langerhans Cells
- Measles
- Measles virus
- Phenotype
- Reference Values
