Article
Langerhans cells are susceptible to measles virus infection and actively suppress T cell proliferation.
European journal of dermatology : EJD - 1 Sept 1998
Steineur M P, Grosjean I, Bella C, Kaiserlian D
Abstract excerpt
We have previously reported that the measles virus (MV) could productively infect human dendritic cells (DC), derived in vitro from CD34+ cord blood progenitors in the presence of GM-CSF and TNF-alpha. In this study, we provide evidence that freshly isolated Langerhans cells (LC), which are immature dendritic cells located in skin and mucosal epithelia, are susceptible to MV infection in vitro as assessed by...
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