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Article

Human cytomegalovirus induces a direct inhibitory effect on antigen presentation by monocyte-derived immature dendritic cells.

British journal of haematology - 1 Oct 2002

Grigoleit Ulrich, Riegler Susanne, Einsele Hermann, Laib Sampaio Kerstin, Jahn Gerhard, Hebart Holger, Brossart Peter, Frank Friderike, Sinzger Christian

Abstract excerpt

The hypothesis that productive infection of monocyte-derived immature dendritic cells (DCs) by the human cytomegalovirus (HCMV) is associated with decreased immunostimulatory capacity was tested in this study. DCs were infected with 60-80% efficiency by HCMV strain TB40/E. Infected versus uninfected cells were analysed by fluorescence-activated cell sorting and by immunocytochemistry for surface expression of...

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Source

Identifiers

PMID: 12358925
DOI: 10.1046/j.1365-2141.2002.03798.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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