Article
Anabaena circadian clock proteins KaiA and KaiB reveal a potential common binding site to their partner KaiC.
The EMBO journal - 21 Apr 2004
Garces Robert G, Wu Ning, Gillon Wanda, Pai Emil F
Abstract excerpt
The cyanobacterial clock proteins KaiA and KaiB are proposed as regulators of the circadian rhythm in cyanobacteria. Mutations in both proteins have been reported to alter or abolish circadian rhythmicity. Here, we present molecular models of both KaiA and KaiB from the cyanobacteria Anabaena sp PCC7120 deduced by crystal structure analysis, and we discuss how clock-changing or abolishing mutations may cause...
Topics
- Amino Acid Sequence
- Anabaena
- Bacterial Proteins
- Binding Sites
- Circadian Rhythm Signaling Peptides and Proteins
- Crystallography, X-Ray
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Binding
- Protein Structure, Quaternary