Article
Identification of a calcineurin-independent pathway required for sodium ion stress response in Saccharomyces cerevisiae.
Genetics - 1 Sept 1998
Ganster R W, McCartney R R, Schmidt M C
Abstract excerpt
The calcium-dependent protein phosphatase calcineurin plays an essential role in ion homeostasis in yeast. In this study, we identify a parallel ion stress response pathway that is independent of the calcineurin signaling pathway. Cells with null alleles in both STD1 and its homologue, MTH1, mani...
Topics
- Adaptation, Physiological
- Base Sequence
- Calcineurin
- DNA Primers
- Fungal Proteins
- Gene Dosage
- Gene Expression Regulation, Fungal
- Glucose
- Homeostasis
- Mutation
- Oxidative Stress
- Phenotype
- Saccharomyces cerevisiae
- Signal Transduction
- Sodium
