Article
A homolog of mammalian, voltage-gated calcium channels mediates yeast pheromone-stimulated Ca2+ uptake and exacerbates the cdc1(Ts) growth defect.
Molecular and cellular biology - 1 Nov 1997
Paidhungat M, Garrett S
Abstract excerpt
Previous studies attributed the yeast (Saccharomyces cerevisiae) cdc1(Ts) growth defect to loss of an Mn2+-dependent function. In this report we show that cdc1(Ts) temperature-sensitive growth is also associated with an increase in cytosolic Ca2+. We identified two recessive suppressors of the cd...
Topics
- Amino Acid Sequence
- Biological Transport
- Calcium
- Calcium Channels
- Cell Cycle Proteins
- Fungal Proteins
- Gene Expression
- Ion Channel Gating
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation
- Pheromones
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid
- Suppression, Genetic