Article
Direct regulation of genes involved in glucose utilization by the calcium/calcineurin pathway.
The Journal of biological chemistry - 16 May 2008
Ruiz Amparo, Serrano Raquel, Ariño Joaquín
Abstract excerpt
Failure to use glucose as carbon source results in transcriptional activation of numerous genes whose expression is otherwise repressed. HXT2 encodes a yeast high affinity glucose transporter that is only expressed under conditions of glucose limitation. We show that HXT2 is rapidly and potently induced by environmental alkalinization, and this requires both the Snf1 and the calcineurin pathways. Regulation by...
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