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Article

Characterization of an allele-nonspecific intragenic suppressor in the yeast plasma membrane H+-ATPase gene (Pma1).

Genetics - 1 Sept 1998

Maldonado A M, de la Fuente N, Portillo F

Abstract excerpt

We have analyzed the ability of A165V, V169I/D170N, and P536L mutations to suppress pma1 dominant lethal alleles and found that the P536L mutation is able to suppress the dominant lethality of the pma1-R271T, -D378N, -D378E, and -K474R mutant alleles. Genetic and biochemical analyses of site-directed mutants at Pro-536 suggest that this amino acid may not be essential for function but is important for biogenesis...

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Identifiers

PMID: 9725826
DOI: 10.1093/genetics/150.1.11
PMCID: PMC1460317

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Source receipt: pubmed, retrieved 7 Sept 2026.

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