Article
Splitting the ATM: distinct repair and checkpoint defects in ataxia-telangiectasia.
Trends in genetics : TIG - 1 Aug 1998
Jeggo P A, Carr A M, Lehmann A R
Abstract excerpt
Ataxia-telangiectasia (A-T) is an autosomal recessive human disorder that, because of its multisystem nature, is of interest to scientists and clinicians from many disciplines. A-T patients have defects in the neurological and immune systems, telangiectasia in the eyes and face, and are, in addition, cancer-prone and radiation-sensitive. A-T cell lines have a range of diverse phenotypes including sensitivity to...
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