Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ataxia‐telangiectasia, cancer and the pathobiology of the <i>ATM</i> gene

1 May 1999

Abstract excerpt

Ataxia-telangiectasia (A-T) is a pleiotropic inherited disease characterized by neurodegeneration, cancer, immunodeficiencies, radiation sensitivity, and genetic instability. Although A-T homozygotes are rare, the A-T gene may play a role in sporadic breast cancer and leukemia. ATM, the gene responsible for A-T, is homologous to several cell cycle checkpoint genes from other organisms. ATM is thought to play a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10422797
DOI: 10.1034/j.1399-0004.1999.550501.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ataxia‐telangiectasia, cancer and the pathobiology of the <i>ATM</i> genePMID 10422797Read ↗

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer.Semantic proximity Read ↗

Ataxia telangiectasia syndrome: moonlighting ATM.Semantic proximity Read ↗

Ataxia-telangiectasia and cellular responses to DNA damage.Semantic proximity Read ↗

Cancer risk and the ATM gene: a continuing debate.Semantic proximity Read ↗

ATM: the product of the gene mutated in ataxia-telangiectasia.Semantic proximity Read ↗

Molecular perspectives on cancer, the cell cycle and the inherited disorder ataxia-telangiectasia.Semantic proximity Read ↗

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functionsSemantic proximity Read ↗

The versatile functions of ATM kinaseSemantic proximity Read ↗

ATM and related protein kinases: safeguarding genome integrity.Semantic proximity Read ↗

What has the cloning of the ATM gene told us about ataxia telangiectasia?Semantic proximity Read ↗

Atm-deficient mice: a paradigm of ataxia telangiectasia.Semantic proximity Read ↗

Ataxia‐telangiectasia: A review of clinical features and molecular pathologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.