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Article

A calcium-dependent ergosterol mutant of Saccharomyces cerevisiae.

Current genetics - 1 Aug 1998

Crowley J H, Tove S, Parks L W

Abstract excerpt

ERG24 is the structural gene for the C14-sterol reductase in yeast. A lack of activity in that enzyme, mediated either by the morpholine fungicides or the insertional inactivation of ERG24, causes the accumulation of the aberrant sterol ignosterol. Cells producing this sterol are unable to grow a...

Topics

Antifungal Agents
Calcium
Culture Media
Ergosterol
Genes, Fungal
Morpholines
Mutation
Oxidoreductases
Phenotype
Saccharomyces cerevisiae

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9724410
DOI: 10.1007/s002940050371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9724410-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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