Article
Regulation of sodium current development in cultured atrial tumor myocytes (AT-1 cells).
The American journal of physiology - 1 Aug 1996
Yang T, Roden D M
Abstract excerpt
AT-1 cells, derived from atrial tumors in transgenic mice, have many features similar to cardiac myocytes. However, their sodium current (INa) has not been evaluated on detail. In this study, two INa phenotypes were identified in AT-1 cells: one at 3 days in culture and the other at 14 days. INa was smaller at 3 days than at 14 days (12 +/- 2 vs. 37 +/- 5 pA/pF) and activated more slowly (time to peak INa at -30...
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