Article
[Free radicals in the origin and clinical manifestation of Down's syndrome].
TSitologiia i genetika - 1 Jan 2000
Arbuzova S B
Abstract excerpt
The high level of free radicals and antioxidant protection disbalancing cause the chromosome nondisjunction in meiosis, appearance of trisomy 21 and fetuses with Down's syndrome, age-dependent pathology, of parent's mosaic clone, clinical manifestations of the syndrome, diseases in relatives, recurrent cases of trisomy 21. The comparative analysis of clinical traits of Down's syndrome and pathological changes in...
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