Article
[Free radicals in the origin and clinical manifestation of Down's syndrome].
TSitologiia i genetika - 1 Jan 2000
Arbuzova S B
Abstract excerpt
The high level of free radicals and antioxidant protection disbalancing cause the chromosome nondisjunction in meiosis, appearance of trisomy 21 and fetuses with Down's syndrome, age-dependent pathology, of parent's mosaic clone, clinical manifestations of the syndrome, diseases in relatives, rec...
Topics
- Abortion, Spontaneous
- Adolescent
- Adult
- Aging
- Antioxidants
- Child
- Down Syndrome
- Female
- Free Radicals
- Humans
- Male
- Nondisjunction, Genetic
- Phenotype
- Pregnancy
- Radiation Injuries