Article
Sequence requirements for terminators and antiterminators in the T box transcription antitermination system: disparity between conservation and functional requirements.
Nucleic acids research - 1 Apr 2002
Grundy Frank J, Moir Tessa R, Haldeman Margaret T, Henkin Tina M
Abstract excerpt
The T box transcription termination control system is used in Gram-positive bacteria to regulate expression of aminoacyl-tRNA synthetase and other amino acid-related genes. Readthrough of a transcriptional terminator located in the leader region of the target gene is dependent on a specific interaction between the nascent leader transcript and the cognate uncharged tRNA. This interaction is required for formation...
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