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Article

tRNA(Trp) translation of leader peptide codon 12 and other factors that regulate expression of the tryptophanase operon.

Journal of bacteriology - 1 Jun 1990

Gollnick P, Yanofsky C

Abstract excerpt

Tryptophanase (tna) operon expression in Escherichia coli is induced by tryptophan. This response is mediated by features of a 319-base-pair leader region preceding the major structural genes of the operon. Translation of the coding region (tnaC) for a 24-amino-acid leader peptide is essential for induction. We have used site-directed mutagenesis to investigate the role of the single Trp codon, at position 12 in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 2345136
DOI: 10.1128/jb.172.6.3100-3107.1990
PMCID: PMC209113

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Source receipt: pubmed, retrieved 7 Sept 2026.

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