Models of natural mutations including site heterogeneity.

Article

Models of natural mutations including site heterogeneity.

Proteins - 15 Aug 1998

Koshi J M, Goldstein R A

Abstract excerpt

New computational models of natural site mutations are developed that account for the different selective pressures acting on different locations in the protein. The number of adjustable parameters is greatly reduced by basing the models on the underlying physical-chemical properties of the amino...

Topics

Evolution, Molecular
Genetic Heterogeneity
HIV-1
HIV-2
Models, Genetic
Mutation
Viral Envelope Proteins

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