Article
Oncogenic Ras modulates epidermal growth factor responsiveness in endometrial carcinomas.
European journal of cancer (Oxford, England : 1990) - 1 Apr 1998
Kato K, Ueoka Y, Kato K, Tamura T, Nishida J, Wake N
Abstract excerpt
Since the majority of endometrial carcinomas do not contain any detectable ras mutations, the precise contribution of aberrant Ras function, if any, to endometrial carcinoma development remains to be determined. Since there is considerable evidence that Ras transformation is associated with a dec...
Topics
- Apoptosis
- Cell Division
- Endometrial Neoplasms
- Enzyme Inhibitors
- Epidermal Growth Factor
- ErbB Receptors
- Female
- Genes, ras
- Humans
- Hydroquinones
- Mutation
- Signal Transduction
- Transforming Growth Factor alpha
- Tumor Cells, Cultured