Phenotypic and biochemical consequences of collagen X mutations in mice and humans.

doi:10.1016/s0945-053x(98)90056-7

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Article

Phenotypic and biochemical consequences of collagen X mutations in mice and humans.

Matrix biology : journal of the International Society for Matrix Biology - 1 Jul 1998

Chan D, Jacenko O

Abstract excerpt

Skeletal biology has entered an exciting period with the technological advances in murine transgenesis and human genetics. This review focuses on how these two approaches are being used to address the role of collagen X, the major extracellular matrix component of the focal zone of endochondral o...

Topics

Animals
Bone and Bones
Cartilage
Collagen
Humans
Mice
Mice, Transgenic
Morphogenesis
Mutation
Osteochondrodysplasias

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