Molecular genetics of chondrodysplasias, including clues to development, structure, and function.

doi:10.1097/00002281-199405000-00018

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Article

Molecular genetics of chondrodysplasias, including clues to development, structure, and function.

Current opinion in rheumatology - 1 May 1994

Byers P H

Abstract excerpt

The extracellular matrix of cartilage consists of many macromolecules. Study of naturally occurring mutations in the genes that encode the chains of type II collagen (COL2A1) and type X collagen (COL10A1) in humans, engineered mutations in those genes in transgenic animals, and naturally occurrin...

Topics

Animals
Cartilage
Chickens
Collagen
Genes
Humans
Macromolecular Substances
Molecular Biology
Mutation
Osteochondrodysplasias
Phenotype
Proteoglycans

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