Article
Molecular genetics of chondrodysplasias, including clues to development, structure, and function.
Current opinion in rheumatology - 1 May 1994
Byers P H
Abstract excerpt
The extracellular matrix of cartilage consists of many macromolecules. Study of naturally occurring mutations in the genes that encode the chains of type II collagen (COL2A1) and type X collagen (COL10A1) in humans, engineered mutations in those genes in transgenic animals, and naturally occurring mutations in the chick aggrecan gene has identified important structural and functional aspects of these gene...
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