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Article

Mutations in collagen genes resulting in metaphyseal and epiphyseal dysplasias.

Bone - 1 Aug 1995

Olsen B R

Abstract excerpt

Genetic mapping and positional cloning of genes, in which mutations lead to osteochondrodysplasias in humans and mice, combined with studies of transgenic mice with mutations in cloned genes, is providing novel and exciting insights into the molecular mechanisms of cartilage and bone development...

Topics

Animals
Bone Development
Camurati-Engelmann Syndrome
Cell Differentiation
Chromosome Mapping
Collagen
Extracellular Matrix
Genes, fos
Genes, src
Genetic Linkage
Growth Plate
Humans
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Mutation

Osteochondrodysplasias

Osteoclasts

Source

Identifiers

PMID: 8579897
DOI: 10.1016/8756-3282(95)00208-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8579897-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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