Measuring departures from Hardy-Weinberg: a Markov chain Monte Carlo method for estimating the inbreeding coefficient.

doi:10.1046/j.1365-2540.1998.00360.x

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Article

Measuring departures from Hardy-Weinberg: a Markov chain Monte Carlo method for estimating the inbreeding coefficient.

Heredity - 1 Jun 1998

Ayres K L, Balding D J

Abstract excerpt

Many well-established statistical methods in genetics were developed in a climate of severe constraints on computational power. Recent advances in simulation methodology now bring modern, flexible statistical methods within the reach of scientists having access to a desktop workstation. We illust...

Topics

Algorithms
Alleles
Animals
Consanguinity
Humans
Inbreeding
Markov Chains
Models, Genetic
Models, Statistical
Monte Carlo Method
New Zealand
Samoa

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