A Bayesian characterization of Hardy-Weinberg disequilibrium.

doi:10.1093/genetics/149.4.2079

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Article

A Bayesian characterization of Hardy-Weinberg disequilibrium.

Genetics - 1 Aug 1998

Shoemaker J, Painter I, Weir B S

Abstract excerpt

A Bayesian method for determining if there are large departures from independence between pairs of alleles at a locus, Hardy-Weinberg equilibrium (HWE), is presented. We endorse the view that a population will never be exactly in HWE and that there will be occasions when there is a need for an al...

Topics

Alleles
Animals
Bayes Theorem
Genetics, Population
Genotype
Humans
Linkage Disequilibrium
Models, Genetic
Probability

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