Article
Quantification of inbreeding due to distant ancestors and its detection using dense single nucleotide polymorphism data.
Genetics - 1 Sept 2011
Keller Matthew C, Visscher Peter M, Goddard Michael E
Abstract excerpt
Inbreeding depression, which refers to reduced fitness among offspring of related parents, has traditionally been studied using pedigrees. In practice, pedigree information is difficult to obtain, potentially unreliable, and rarely assessed for inbreeding arising from common ancestors who lived more than a few generations ago. Recently, there has been excitement about using SNP data to estimate inbreeding (F)...
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