Article
Regulation of human alcohol dehydrogenase gene ADH7: importance of an AP-1 site.
DNA and cell biology - 1 Jul 1998
Kotagiri S, Edenberg H J
Abstract excerpt
The structure and function of the human alcohol dehydrogenase 7 (ADH7) promoter were analyzed. A promoter fragment extending to bp -232 functioned well in H4IIE-C3, CV-1, and HeLa cells, whereas the region extending further upstream to bp -799 had no significant effect on activity. We identified...
Topics
- Alcohol Dehydrogenase
- Animals
- Base Sequence
- Binding Sites
- CCAAT-Enhancer-Binding Proteins
- Cell Line
- DNA
- DNA-Binding Proteins
- Gene Expression
- Gene Expression Regulation, Enzymologic
- Genes
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Protein Binding