Article
Susceptibility to melanoma: influence of skin type and polymorphism in the melanocyte stimulating hormone receptor gene.
The Journal of investigative dermatology - 1 Aug 1998
Ichii-Jones F, Lear J T, Heagerty A H, Smith A G, Hutchinson P E, Osborne J, Bowers B, Jones P W, Davies E, Ollier W E, Thomson W, Yengi L, Bath J, Fryer A A, Strange R C
Abstract excerpt
Allelic variation at the melanocyte stimulating hormone receptor (MC1R) gene has been linked with sun-sensitive skin types, suggesting it is a susceptibility candidate for melanoma. We determined the frequency of the val92met, asp294his, and asp84glu MC1R alleles in 190 Caucasian controls and 306...
Topics
- Adult
- Aged
- Alleles
- Disease Susceptibility
- Hair Color
- Humans
- Melanoma
- Middle Aged
- Polymorphism, Genetic
- Receptors, Pituitary Hormone
- Skin
- Skin Neoplasms
