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Article

p21/WAF1, p53 and PCNA expression and p53 mutation status in hepatocellular carcinoma.

International journal of cancer - 21 Aug 1998

Qin L F, Ng I O, Fan S T, Ng M

Abstract excerpt

The cyclin-dependent kinase inhibitor p21/WAF1 is regulated by p5S3-dependent and p53-independent pathways. In addition, p21/WAF1 binds with proliferating cell nuclear antigen (PCNA) and inhibits the action of PCNA. To investigate the possible role of p21/WAF1 in human hepatocellular carcinomas (HCCs), we examined the expression of p21/WAF1 and its relation with PCNA and p53 expression in 97 surgically resected...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9699537
DOI: 10.1002/(sici)1097-0215(19980821)79:4<424::aid-ijc19>3.0.co;2-4

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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p21/WAF1, p53 and PCNA expression and p53 mutation status in hepatocellular carcinoma.PMID 9699537Read ↗

P21WAF1/Cip1 gene expression in primary human hepatocellular carcinoma and its relationship with P53 gene mutation.Semantic proximity Read ↗

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