Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p21 expression predicts outcome in p53-null ovarian carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2003

Rose Stephen L, Goodheart Michael J, DeYoung Barry R, Smith Brian J, Buller Richard E

Abstract excerpt

PURPOSE: p21 is a direct p53 response gene. Although several studies have correlated p21 and p53 expression, only one has evaluated p21 expression as a function of sequenced p53 gene mutation. We hypothesize that such an analysis may be useful in prognosticating outcome for individuals diagnosed with epithelial ovarian cancer. EXPERIMENTAL DESIGN: DNA from the primary ovarian cancers of 267 patients was studied....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Cell Cycle

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Division

Share to Genes, p53

Share to Multivariate Analysis

Share to Ovarian Neoplasms

Share to Proportional Hazards Models

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 12631602

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p21 expression predicts outcome in p53-null ovarian carcinoma.PMID 12631602Read ↗

p21 expression in colorectal carcinomas: a study on 103 cases with analysis of p53 gene mutation/expression and clinic-pathological correlations.Semantic proximity Read ↗

Deregulated p21(WAF1) overexpression impacts survival of surgically resected esophageal squamous cell carcinoma patients.Semantic proximity Read ↗

Relationship between p21 expression and mutation of the p53 tumor suppressor gene in normal and malignant ovarian epithelial cells.Semantic proximity Read ↗

p21WAF1 immunohistochemical expression in breast carcinoma: correlations with clinicopathological data, oestrogen receptor status, MIB1 expression, p53 gene and protein alterations and relapse-free survival.Semantic proximity Read ↗

A review of p53 expression and mutation in human benign, low malignant potential, and invasive epithelial ovarian tumors.Semantic proximity Read ↗

P53 mutation in a series of epithelial ovarian cancers from the U.K., and its prognostic significance.Semantic proximity Read ↗

Expression and sequence analysis of the p21(WAF1/CIP1) gene in renal cancers.Semantic proximity Read ↗

Relationship between abnormal p53 protein and failure to express p21 protein in human breast carcinomas.Semantic proximity Read ↗

p21/WAF1, p53 and PCNA expression and p53 mutation status in hepatocellular carcinoma.Semantic proximity Read ↗

p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma.Semantic proximity Read ↗

p21/WAF1 cyclin-kinase inhibitor expression in non-Hodgkin's lymphomas: a potential marker of p53 tumor-suppressor gene function.Semantic proximity Read ↗

Clinical and pathological associations with p53 tumour-suppressor gene mutations and expression of p21WAF1/Cip1 in colorectal carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.