Article
p21 expression predicts outcome in p53-null ovarian carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2003
Rose Stephen L, Goodheart Michael J, DeYoung Barry R, Smith Brian J, Buller Richard E
Abstract excerpt
PURPOSE: p21 is a direct p53 response gene. Although several studies have correlated p21 and p53 expression, only one has evaluated p21 expression as a function of sequenced p53 gene mutation. We hypothesize that such an analysis may be useful in prognosticating outcome for individuals diagnosed...
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