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Article

Tetraploid embryos rescue embryonic lethality caused by an additional maternally inherited X chromosome in the mouse.

Development (Cambridge, England) - 1 Sept 1998

Goto Y, Takagi N

Abstract excerpt

Mouse embryos with an additional maternally inherited X chromosome, i.e., disomic for XM (DsXM), cease to grow early in development and have a deficient extraembryonic region. We hypothesized that the underdeveloped extraembryonic region is attributed to two copies of XM that escape inactivation due to maternal imprinting. To examine the validity of this hypothesis and throw more light on the significance of X...

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Identifiers

PMID: 9693139
DOI: 10.1242/dev.125.17.3353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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