Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Informational suppressor alleles of the eEF1A gene, fertility and cell degeneration in Podospora anserina.

Molecular & general genetics : MGG - 1 Oct 2000

Silar P, Rossignol M, Tahar R, Derhy Z, Mazabraud A

Abstract excerpt

Mutations that increase readthrough at a UGA stop codon (informational suppressor mutations) were created in the gene (AS4) that encodes translation elongation factor eEF1A in the filamentous fungus Podospora amserina. The results strongly suggest that the net charge of the eEF1A protein controls the accuracy of translation. Physiological analysis of the mutant strains shows that some of the alleles dominantly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Codon, Terminator
Share to DNA Replication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to Genes, Suppressor

Share to Peptide Elongation Factor 1

Share to Protein Biosynthesis

Source

Identifiers

PMID: 11085276
DOI: 10.1007/s004380000337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Informational suppressor alleles of the eEF1A gene, fertility and cell degeneration in Podospora anserina.PMID 11085276Read ↗

eEF1A Controls ascospore differentiation through elevated accuracy, but controls longevity and fruiting body formation through another mechanism in Podospora anserina.Semantic proximity Read ↗

Identification of the genes encoding the cytosolic translation release factors from Podospora anserina and analysis of their role during the life cycle.Semantic proximity Read ↗

Up-regulation of tRNA biosynthesis affects translational readthrough in maf1-delta mutant of Saccharomyces cerevisiae.Semantic proximity Read ↗

Loss of Elongation-Like Factor 1 Spontaneously Induces Diverse, RNase H-Related Suppressor Mutations in Schizosaccharomyces pombe.Semantic proximity Read ↗

Cytosolic ribosomal mutations that abolish accumulation of circular intron in the mitochondria without preventing senescence of Podospora anserina.Semantic proximity Read ↗

Increased longevity of EF-1 alpha high-fidelity mutants in Podospora anserina.Semantic proximity Read ↗

The snpA, a temperature-sensitive suppressor of npgA1, encodes the eukaryotic translation release factor, eRF1, in Aspergillus nidulans.Semantic proximity Read ↗

Spatio-temporal patterning of arginyl-tRNA protein transferase (ATE) contributes to gametophytic development in a moss.Semantic proximity Read ↗

The Podospora rmp1 gene implicated in nucleus-mitochondria cross-talk encodes an essential protein whose subcellular location is developmentally regulated.Semantic proximity Read ↗

SSL1, a suppressor of a HIS4 5'-UTR stem-loop mutation, is essential for translation initiation and affects UV resistance in yeast.Semantic proximity Read ↗

Genetic analysis of L123 of the tRNA-mimicking eukaryote release factor eRF1, an amino acid residue critical for discrimination of stop codons.Semantic proximity Read ↗

Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.