Article
Methylenetetrahydrofolate reductase polymorphism affects the change in homocysteine and folate concentrations resulting from low dose folic acid supplementation in women with unexplained recurrent miscarriages.
The Journal of nutrition - 1 Aug 1998
Nelen W L, Blom H J, Thomas C M, Steegers E A, Boers G H, Eskes T K
Abstract excerpt
To determine the effects of daily supplementation of 0.5 mg folic acid on homocysteine and folate concentrations, we investigated 49 women with a history of unexplained recurrent miscarriages. A methionine loading test (including the vitamin concentrations of concern) was used preceding and after...
Topics
- Abortion, Habitual
- Adult
- Dietary Supplements
- Erythrocytes
- Female
- Folic Acid
- Genotype
- Homocysteine
- Homozygote
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Oxidoreductases Acting on CH-NH Group Donors
- Polymorphism, Genetic
- Pregnancy