Article
The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations.
Reproductive toxicology (Elmsford, N.Y.) - 1 Sept 2017
Serapinas Danielius, Boreikaite Evelina, Bartkeviciute Agne, Bandzeviciene Rita, Silkunas Mindaugas, Bartkeviciene Daiva
Abstract excerpt
In patients with MTHFR (methylenetetrahydrofolate reductase) mutations and hyperhomocysteinemia, recurrent pregnancy loss is a frequent feature. The aim of the study was to evaluate the impact of folic acid, vitamins B6 and B12 supplementation for the lowering of total homocysteine concentrations and pregnancy. 16 patients who had had 3 or more miscarriages and MTHFR mutations were used in the study. They...
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