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Article

Folate and homocysteine phenotypes: Comparative findings using research and clinical laboratory data.

Clinical biochemistry - 1 Aug 2009

Mitchell Laura E, Morales Megan, Khartulyari Stefanie, Huang Yuehua, Murphy Kristen, Mei Minghua, Von Feldt Joan M, Blair Ian A, Whitehead Alexander S

Abstract excerpt

OBJECTIVES: A low folate/high homocysteine phenotype is associated with several pathologies, including spina bifida and cardiovascular disease. Folate and total homocysteine (tHcy) measurements are used clinically to assess risk and the need for folic acid supplementation and in research to investigate the metabolic basis of disease. Red blood cell (RBC) folate, the best indicator of long-term folate status, is...

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Identifiers

PMID: 19427846
DOI: 10.1016/j.clinbiochem.2009.04.014
PMCID: PMC4051207

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