Article
Inherited platelet glycoprotein polymorphisms and a risk for coronary heart disease in young central Europeans.
Thrombosis research - 1 May 1998
Sperr W R, Huber K, Roden M, Janisiw M, Lang T, Graf S, Maurer G, Mayr W R, Panzer S
Abstract excerpt
Among central Europeans polymorphisms of GPIIIa, GPIb, GPIIb, and GPIa named human platelet antigen-1 (HPA-1), -2, -3, and -5 are the clinically most relevant systems in which alloimmunization occurs. These genetically determined polymorphisms of glycoproteins may render platelets sensible for pl...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Antigens, Human Platelet
- Coronary Disease
- Diabetes Mellitus
- Diabetic Angiopathies
- Europe
- Female
- Gene Frequency
- Humans
- Male
- Middle Aged
- Platelet Membrane Glycoproteins
- Polymorphism, Genetic
- Risk Factors