Article
Inherited platelet glycoprotein polymorphisms and a risk for coronary heart disease in young central Europeans.
Thrombosis research - 1 May 1998
Sperr W R, Huber K, Roden M, Janisiw M, Lang T, Graf S, Maurer G, Mayr W R, Panzer S
Abstract excerpt
Among central Europeans polymorphisms of GPIIIa, GPIb, GPIIb, and GPIa named human platelet antigen-1 (HPA-1), -2, -3, and -5 are the clinically most relevant systems in which alloimmunization occurs. These genetically determined polymorphisms of glycoproteins may render platelets sensible for plaque formation and thus could increase risk for coronary artery disease (CAD). We therefore determined gene frequencies...
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